<p>Isolated human antibodies or antigen-binding fragments thereof, which specifically bind to human RANKL and block hRANKL binding to a RANK receptor, are provided. The antibodies are useful in preventing or treating disorders and/or diseases, which are associated with RANKL/RANK interactions, including bone disorders or cancer.</p>
申请公布号
WO2010022120(A1)
申请公布日期
2010.02.25
申请号
WO2009US54262
申请日期
2009.08.19
申请人
REGENERON PHARMACEUTICALS, INC.;MARTIN, JOEL, H.;ECONOMIDES, ARIS, N.;RAZ, REGINA