| 摘要 |
(2S,3R,4S)-4-hydroxyisoleucine or a chemically acceptable salt thereof may be purified and separated by: (a) reacting (2S,3R,4S)-4-hydroxyisoleucine or a chemically acceptable salt thereof in a mixture with an aldehyde compound represented by formula: Q-CHO, wherein Q is an aryl group having 6 to 14 carbon atoms, an alkyl group having 1 to 10 carbon atoms, a cycloalkyl group having 3 to 10 carbon atoms, or a 5- to 10-membered heterocyclic group, each of which optionally has one or more substituents, or an equivalent form thereof to obtain a compound represented by formula (1) wherein Q is as defined above; (b) extracting the compound represented by formula (1) with an organic solvent; and (c) converting the compound represented by formula (1) to (2S,3R,4S)-4-hydroxyisoleucine or a chemically acceptable salt thereof.
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