NOVEL USE OF LIPOCALIN 2 FOR TREATING BRAIN DAMAGE

摘要

The present invention relates to a composition containing a lipocalin 2 (LCN2) inhibitor for treating brain damage and a method for treating brain damage by administering the composition. When the central nervous system (CNS) is injured, astrocytes are activated and astrocytosis is induced. Astrocytosis is a main factor causing nerve cell damage and suppressing regeneration of damaged nerve cells. Since the LCN2 mainly induces astrocytosis, additional damage of nerve cells after brain damage is prevented using the LCN2 inhibitor. Also, the regeneration of damaged nerve cells can be promoted.