发明名称 IL1RL-1 AS CARDIOVASCULAR DISEASE MARKER AND THERAPEUTIC TARGET
摘要 <P>PROBLEM TO BE SOLVED: To provide a method and a composition for diagnosis and treatment of cardiovascular conditions. <P>SOLUTION: The method for diagnosing cardiovascular conditions, characterized by aberrant expression of a nucleic acid molecule or an expression product thereof, includes (a) a step of bringing a biological sample obtained from a subject into contact with an agent which specifically binds to the nucleic acid molecule, an expression product thereof, or a fragment of the expression product; and (b) a step of measuring the amount of the bound agent, and determining therefrom whether the expression of the nucleic acid molecule or of the expression product is aberrant, the aberrant expression being diagnostic of the disorder. In the method, the nucleic acid molecule is at least one nucleic acid molecule selected from the group consisting of specific sequences. <P>COPYRIGHT: (C)2010,JPO&INPIT
申请公布号 JP2010041998(A) 申请公布日期 2010.02.25
申请号 JP20090173539 申请日期 2009.07.24
申请人 BRIGHAM & WOMEN'S HOSPITAL INC 发明人 LEE RICHARD T
分类号 C12Q1/68;G01N33/50;A61K38/00;A61K45/00;A61K45/06;A61P9/00;A61P9/04;A61P9/10;A61P43/00;C12N15/09;G01N33/15;G01N33/53;G01N33/566;G01N33/68 主分类号 C12Q1/68
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