发明名称 Transgenic non-human animal models of apoptosis-mediated conditions
摘要 A transgenic non-human animal whose genome comprises a stable integration of a transgene that encodes at least one Fas-ligand protein operably-linked to a tetracycline-inducible promoter includes cells that express the transgene and undergo apoptosis. The transgenic non-human animal can be used to screen for compounds that inhibit apoptosis and to identify cells that are capable of differentiating in vivo.
申请公布号 US2010050276(A1) 申请公布日期 2010.02.25
申请号 US20080229438 申请日期 2008.08.22
申请人 BROWN UNIVERSITY 发明人 DEPAEPE MONIQUE E.
分类号 A01K67/027;C12N15/11 主分类号 A01K67/027
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