发明名称 |
CROSSLINKED CATION EXCHANGE POLYMERS, COMPOSITIONS AND USE IN TREATING HYPERKALEMIA |
摘要 |
The present invention is directed to crosslinked cation exchange polymers comprising a fluoro group and an acid group, pharmaceutical compositions of these polymers, compositions of a linear polyol and a salt of such polymer. Crosslinked cation exchange polymers having beneficial physical properties, including combinations of particle size, particle shape, particle size distribution, viscosity, yield stress, compressibility, surface morphology, and/or swelling ratio are also described. These polymers and compositions are useful to bind potassium in the gastrointestinal tract.
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申请公布号 |
CA2735058(A1) |
申请公布日期 |
2010.02.25 |
申请号 |
CA20092735058 |
申请日期 |
2009.08.22 |
申请人 |
RELYPSA, INC. |
发明人 |
MANSKY, PAUL;ALBRECHT, DETLEF;BURDICK, MICHAEL;CHANG, HAN-TING;CHARMOT, DOMINIQUE;CONNOR, ERIC;HALFON, SHERIN;HUANG, I-ZU;LIU, MINGJUN;CHIDAMBARAM, RAMAKRISHNAN;MILLS, JONATHAN;STRUEVER, WERNER |
分类号 |
C08F4/68;A61K31/78;A61P7/08 |
主分类号 |
C08F4/68 |
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