发明名称 |
Novel tyrosinase-specific anti-gene oligonucleotides as depigmenting agents |
摘要 |
The present invention relates to an anti-gene oligonucleotide which hybridizes specifically with the gene encoding human tyrosinase by Hoogsteen pairing between the complementary bases, said oligonucleotide forming a triple helix structure with the human tyrosinase gene. The invention also relates to the use of said oligonucleotide as a skin-depigmenting or skin-bleaching agent in a cosmetic composition or in a dermatological composition.
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申请公布号 |
US2010047192(A1) |
申请公布日期 |
2010.02.25 |
申请号 |
US20060991317 |
申请日期 |
2006.09.01 |
申请人 |
L.V.M.H. RECHERCHE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS);MUSEUM NATIONAL D'HISTOIRE NATURELLE |
发明人 |
KURFUERST ROBIN;BONNET-DUQUENNOY MATHILDE;LAZOU KRISTELL;GIOVANNANGELI CARINE |
分类号 |
A61K8/60;A61K31/7088;A61Q17/04;A61Q19/02;C07H21/00;C12N15/113 |
主分类号 |
A61K8/60 |
代理机构 |
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地址 |
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