发明名称 |
TREATMENT OF AN AUTOIMMUNE DISEASE USING IL-18 ANTAGONISTS |
摘要 |
The present invention relates to the field of autoimmune diseases, including rheumatoid arthritis (RA) and inflammatory bowel disease (IBD). Specifically, the invention relates to methods of treating autoimmune diseases in patients that are non- responsive or refractory over time to treatment with TNF-a antagonists and/or T-cell co-stimulation antagonists with an IL-18 antagonist.
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申请公布号 |
CA2734358(A1) |
申请公布日期 |
2010.02.25 |
申请号 |
CA20092734358 |
申请日期 |
2009.08.14 |
申请人 |
GLAXO GROUP LIMITED |
发明人 |
OVEREND, PHILIP;REID, JULIET LOUISE;ROCHA DEL CURA, MARIA DE LOS ANGELES;TAYLOR, ADAM RENE |
分类号 |
A61K31/00;A61K39/395;A61P3/10;A61P17/06;A61P37/00;A61P43/00 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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