发明名称 TREATMENT OF AN AUTOIMMUNE DISEASE USING IL-18 ANTAGONISTS
摘要 The present invention relates to the field of autoimmune diseases, including rheumatoid arthritis (RA) and inflammatory bowel disease (IBD). Specifically, the invention relates to methods of treating autoimmune diseases in patients that are non- responsive or refractory over time to treatment with TNF-a antagonists and/or T-cell co-stimulation antagonists with an IL-18 antagonist.
申请公布号 CA2734358(A1) 申请公布日期 2010.02.25
申请号 CA20092734358 申请日期 2009.08.14
申请人 GLAXO GROUP LIMITED 发明人 OVEREND, PHILIP;REID, JULIET LOUISE;ROCHA DEL CURA, MARIA DE LOS ANGELES;TAYLOR, ADAM RENE
分类号 A61K31/00;A61K39/395;A61P3/10;A61P17/06;A61P37/00;A61P43/00 主分类号 A61K31/00
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