发明名称 HETEROARYL SUBSTITUTED TETRAZOLE MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR-5
摘要 Tetrazole compounds substituted directly, or by a bridge, with a heteroaryl moiety containing N adjacent to the point of connection of the heteroaryl of formula (I): (see formula I) and pharmaceutically acceptable salts thereof are mGluR5 modulators useful in the treatment of psychiatric and mood disorders such as, for example, schizophrenia, anxiety, depression, and panic, as well as in the treatment of pain and other diseases.
申请公布号 CA2462289(C) 申请公布日期 2010.02.23
申请号 CA20022462289 申请日期 2002.10.01
申请人 MERCK & CO., INC. 发明人 COSFORD, NICHOLAS D.;ROPPE, JEFFREY;CHEN, CHIXU;SMITH, NICHOLAS;REGER, THOMAS
分类号 C07D401/04;A61K31/135;A61K31/41;A61K31/4155;A61K31/4178;A61K31/4184;A61K31/42;A61K31/422;A61K31/4439;A61K31/4709;A61K31/4725;A61K31/485;A61K31/497;A61K45/00;A61P3/04;A61P25/04;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P25/30;A61P25/34;A61P29/00;C07D401/14;C07D403/04;C07D403/14;C07D405/04;C07D405/14;C07D413/04;C07D413/14;C07D417/04;C07D417/14;C07D471/04 主分类号 C07D401/04
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