发明名称 |
Construction of chimera PRRSV, compositions and vaccine preparations |
摘要 |
Chimeric replicons of North American Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) containing the 5′ sequence of an avirulent strain of PRRSV and a 3′ sequence of a virulent strain of PRRSV are provided. Further provided is a method of producing attenuated PRRSV from the chimeric replicon. Also provided are compositions containing the replicon or attenuated virus. Vaccines and a method of vaccinating pigs against PRRSV are also provided.
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申请公布号 |
US7666585(B2) |
申请公布日期 |
2010.02.23 |
申请号 |
US20070763822 |
申请日期 |
2007.06.15 |
申请人 |
PROTATEK INTERNATIONAL, INC. |
发明人 |
ZHANG XUEXIAN;MA SHI-JUN |
分类号 |
C12Q1/70 |
主分类号 |
C12Q1/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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