| 摘要 |
The present invention provides a compound of formula (I) and the use thereof for the treatment of a central nervous system disorder related to or affected by the histamine-3 receptor, wherein Rand Rare taken together with the atom to which they are attached to form an optionally substituted monocyclic 5-membered aromatic ring system optionally containing one or two additional heteroatoms selected from N, O or S or an optionally substituted fused bicyclic or tricyclic 9-to 15-membered aromatic ring system optionally containing one to three additional heteroatoms selected from N, O or S; and where R, R, R, Rand x are as defined herein.
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