EX VIVO THERAPEUTIC SCREENING OF LIVING BONE MARROW CELLS FOR MULTIPLE MYELOMA

摘要

Methods of selecting a treatment for a patient with multiple myeloma are provided. Prior to commencing a treat-ment regime, bone marrow aspirates are isolated from a patient and incubated with one or more candidate therapeutics. The meth-ods identify the therapy or combination of therapies most likely to yield the best results for a particular individual. In addition to improving clinical outcome, such theranostic evaluations dramatically reduce health care costs, by avoiding ineffective therapies. Screening assays for identifying treatments for multiple myeloma also are provided.