发明名称 MONOARYL AMINOTETRALINES
摘要 The invention is concerned with the compounds of formula (I): and pharmaceutically acceptable salts and esters thereof, wherein R1, R2 and R3 are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds of formula (I) are antagonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma.
申请公布号 WO2010018112(A2) 申请公布日期 2010.02.18
申请号 WO2009EP60156 申请日期 2009.08.05
申请人 F. HOFFMANN-LA ROCHE AG;BLANC, JEAN-BAPTISTE;CHEN, LI;FIROOZNIA, FARIBORZ;GILLESPIE, PAUL;GOODNOW JR., ROBERT ALAN;LIN, TAI-AN;PAN, SONG;SO, SUNG-SAU;YUN, HONGYING 发明人 BLANC, JEAN-BAPTISTE;CHEN, LI;FIROOZNIA, FARIBORZ;GILLESPIE, PAUL;GOODNOW JR., ROBERT ALAN;LIN, TAI-AN;PAN, SONG;SO, SUNG-SAU;YUN, HONGYING
分类号 C07C311/20;A61K31/18;A61K31/40;A61P11/00;C07C311/29;C07D207/12 主分类号 C07C311/20
代理机构 代理人
主权项
地址