发明名称 |
HYBRIDIZATION-STABILIZING CONSTRUCT |
摘要 |
A Z-shaped construct having the capacity to hybridize to double stranded DNA in a trans fashion to affect transcription is produced from at least two oligonucleotides, connected to each other, wherein the oligonucleotides are connected to one another through one of sequence specific Watson-Crick base pairing; a covalent linker or a covalent bond directly between the backbones or the bases of said oligonucleotides; or a non-covalent linker or a non-covalent bond directly between the backbones or the bases of said oligonucleotides.
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申请公布号 |
US2010041738(A1) |
申请公布日期 |
2010.02.18 |
申请号 |
US20060993018 |
申请日期 |
2006.06.20 |
申请人 |
AVARIS AB |
发明人 |
SMITH EDVARD;SVAHN MATHIAS;GE RONGBIN |
分类号 |
A61K31/7088;C12N15/11;C12N15/63 |
主分类号 |
A61K31/7088 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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