SITE SPECIFIC FLUORESCENCE MARKING AND CONTRAST MARKER FOR SAME
摘要
A contrast marker for indicating a presence of a target cell in an environment comprises a fluorophore, an NMP, and a short spacer and a long spacer linking the fluorophore to the NMP. The short spacer holds the fluorophore at a quenching distance from the NMP and the long spacer holds the fluorophore at a fluorescence enhancing distance from the NMP. The short spacer is configured to be cleaved by a molecule characterizing the target cells.
申请公布号
WO2009139972(A3)
申请公布日期
2010.02.18
申请号
WO2009US39025
申请日期
2009.03.31
申请人
UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.;KANG, KYUNG, A.;NANTZ, MICHAEL, H.