发明名称 |
PROTEIN-BINDING METHOTREXATE DERIVATIVES, AND MEDICAMENTS CONTAINING THE SAME |
摘要 |
The invention relates to methotrexate derivatives which contain a protein-binding group and can be enzymatically cleaved in the body such that the active substance or a low-molecular active substance derivative is released. Also disclosed is a method for producing methotrexate derivatives, the use thereof, and medicaments comprising methotrexate derivative. |
申请公布号 |
US2010041615(A1) |
申请公布日期 |
2010.02.18 |
申请号 |
US20070375406 |
申请日期 |
2007.07.25 |
申请人 |
MEDAC GESELLSCHAFT FUR KLINISCHE SPEZIALPRAPARATEMBH |
发明人 |
KRATZ FELIX;WARNECKE ANDRE |
分类号 |
A61K38/07;C07K5/10 |
主分类号 |
A61K38/07 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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