APPARATUS AND METHOD FOR A MICROFLUIDIC SYSTEM FOR CREATING A CONCENTRATION GRADIENT

摘要

The present invention relates to a microfluidic device (200) for creating a concentration gradient which includes a microfluidic channel (202) including two or more inlets for introducing fluid solutions, two or more channel segments (208, 224, 226, 228), a ridged element (210, 216, 218, 220) including a plurality of ridges (212) in and/or on an interior wall (214) in at least one segment, wherein the ridged element (210, 216, 218, 220) creates a localized secondary flow effect and a local mixing effect in the at least one segment of the channel (202) for the formation of a concentration gradient over the width of the channel (202).