发明名称 BI-ARYL AMINOTETRALINES
摘要 The invention is concerned with the compounds of formula (I) and pharmaceutically acceptable salts and esters thereof, wherein R1-R5, A, B, Q, W, and X are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and us-ing the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds of formu-la (I) are antagonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma.
申请公布号 CA2735392(A1) 申请公布日期 2010.02.18
申请号 CA20092735392 申请日期 2009.08.05
申请人 F. HOFFMANN-LA ROCHE AG 发明人 BLANC, JEAN-BAPTISTE;CHEN, LI;FIROOZNIA, FARIBORZ;GILLESPIE, PAUL;GOODNOW, ROBERT ALAN JR.;HE, YUN;LIN, TAI-AN;SO, SUNG-SAU;YUN, HONGYING;ZHANG, ZHENSHAN
分类号 C07C311/20;A61K31/18;A61K31/395;A61P11/00;C07C311/29;C07C323/67;C07D213/34;C07D213/71 主分类号 C07C311/20
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