发明名称 |
BI-ARYL AMINOTETRALINES |
摘要 |
The invention is concerned with the compounds of formula (I) and pharmaceutically acceptable salts and esters thereof, wherein R1-R5, A, B, Q, W, and X are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and us-ing the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds of formu-la (I) are antagonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma.
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申请公布号 |
CA2735392(A1) |
申请公布日期 |
2010.02.18 |
申请号 |
CA20092735392 |
申请日期 |
2009.08.05 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
BLANC, JEAN-BAPTISTE;CHEN, LI;FIROOZNIA, FARIBORZ;GILLESPIE, PAUL;GOODNOW, ROBERT ALAN JR.;HE, YUN;LIN, TAI-AN;SO, SUNG-SAU;YUN, HONGYING;ZHANG, ZHENSHAN |
分类号 |
C07C311/20;A61K31/18;A61K31/395;A61P11/00;C07C311/29;C07C323/67;C07D213/34;C07D213/71 |
主分类号 |
C07C311/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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