发明名称 |
PURINE DERIVATIVES FOR USE IN THE TREATMENT OF ALLERGIC, INFLAMMATORY AND INFECTIOUS DISEASES |
摘要 |
Compounds of Formula (I): wherein R1 is C1-6alkylamino, C1-6alkoxy, or C3-7cycloalkyloxy; m is an integer having a value of 2 to 6; R2 is hydrogen, C1-6alkyl, or C3-7cycloalkylC0-6alkyl; and salts thereof are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment of various disorders, for example the treatment of allergic diseases and other inflammatory conditions for example allergic rhinitis and asthma, the treatment of infectious diseases and cancer, and may also be useful as vaccine adjuvants.
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申请公布号 |
CA2733743(A1) |
申请公布日期 |
2010.02.18 |
申请号 |
CA20092733743 |
申请日期 |
2009.08.07 |
申请人 |
GLAXOSMITHKLINE LLC |
发明人 |
BAZIN-LEE, HELENE;BIGGADIKE, KEITH;COE, DIANE MARY;LEWELL, XIAO QING;MITCHELL, CHARLOTTE JANE;TRIVEDI, NAIMISHA |
分类号 |
C07D473/16;A61K31/522;A61P35/00;A61P37/00;C07D473/18 |
主分类号 |
C07D473/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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