发明名称 PURINE DERIVATIVES FOR USE IN THE TREATMENT OF ALLERGIC, INFLAMMATORY AND INFECTIOUS DISEASES
摘要 Compounds of formula (I): wherein R1 is C1-6alkylamino, C1-6alkoxy, or C3-7cycloalkyloxy; m is an integer having a value of 3 to 6; n is an integer having a value of 0 to 4; and salts thereof are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment of various disorders, for example the treatment of allergic diseases and other inflammatory conditions for example allergic rhinitis and asthma, the treatment of infectious diseases and cancer, and may also be useful as vaccine adjuvants.
申请公布号 CA2733749(A1) 申请公布日期 2010.02.18
申请号 CA20092733749 申请日期 2009.08.07
申请人 GLAXOSMITHKLINE LLC 发明人 BIGGADIKE, KEITH;COE, DIANE MARY;LEWELL, XIAO QING;MITCHELL, CHARLOTTE JANE;SMITH, STEPHEN ALLAN;TRIVEDI, NAIMISHA
分类号 C07D473/18;A61K31/522;A61P35/00;A61P37/00;C07D473/16 主分类号 C07D473/18
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