发明名称 |
MEANS AND METHODS FOR CLASSIFYING SAMPLES OF MULTIPLE SCLEROSIS PATIENTS |
摘要 |
The invention relates to a method for classifying cells from a human individual that are typically responsive to exposure to a type I interferon by determining a level of activity of a pathway that is modulated by said type 1 interferon. In one embodiment, said individual is suffering from, or at risk of suffering from, an autoimmune disease, such as, for example, multiple sclerose. In a preferred embodiment, the level of activity is determined by determining an expression level of at least one gene of Table 2 in said cells. The invention further relates to a kit for detecting said at least one gene of Table 2, and use of said kit. |
申请公布号 |
EP2153226(A2) |
申请公布日期 |
2010.02.17 |
申请号 |
EP20080766766 |
申请日期 |
2008.06.02 |
申请人 |
VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS, WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG |
发明人 |
VAN BAARSEN, ELISABETH GEERTRUIDA MARIA;STAHLECKER-VOSLAMBER, SASKIA;VERWEIJ, CORNELIS LAMMERT;POLMAN, CHRIS, HUBERT |
分类号 |
G01N33/50;G01N33/564;G01N33/68 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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