发明名称 |
Hydroxyalkyl starch derivatives |
摘要 |
<p>The present invention relates to a method of producing a hydroxyalkyl starch derivative comprising reacting hydroxyalkyl starch of formula (I)
at its reducing end which is not oxidized prior to said reaction, with a compound of formula (II)
€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ R'-NH-R"€ƒ€ƒ€ƒ€ƒ€ƒ(II)
wherein R 1 , R 2 and R 3 are independently hydrogen or a linear or branched hydroxyalkyl group, and wherein either R' or R" or R' and R" comprise at least one functional group X capable of being reacted with at least one other compound prior to or after the reaction of (I) and (II), as well as to the hydroxyalkyl starch derivative as such, obtainable by said method, and to a pharmaceutical composition comprising said hydroxyalkyl starch derivative.</p> |
申请公布号 |
EP2154160(A1) |
申请公布日期 |
2010.02.17 |
申请号 |
EP20090014352 |
申请日期 |
2003.09.11 |
申请人 |
FRESENIUS KABI DEUTSCHLAND GMBH |
发明人 |
ZANDER, NORBERT;EICHNER, WOLFRAM;CONRADT, HARALD |
分类号 |
C08B31/12;A61K8/73;A61K9/00;A61K9/14;A61K38/00;A61K38/18;A61K47/48;C07K14/505;C07K14/53;C07K14/54;C07K14/55;C07K14/56;C07K14/565;C07K17/06;C07K17/10;C08B31/00;C08B31/08;C08B33/04;C08B35/04;C12N15/12 |
主分类号 |
C08B31/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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