发明名称 CSF-1R INHIBITORS, COMPOSITIONS, AND METHODS OF USE
摘要 Benzoxazole and benzothiazole compounds and their oxides, esters, prodrugs, solvates, and pharmaceutically acceptable salts thereof are disclosed. Compositions of the compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier, and uses of the compounds, either alone or in combination with at least one additional therapeutic agent are also disclosed. The embodiments are useful for inhibiting cellular proliferation, inhibiting the growth and/or metathesis of tumors, treating or preventing cancer, treating or preventing degenerating bone diseases such as rheumatoid arthritis, and/or inhibiting molecules such as CSF 1R.
申请公布号 KR20100017866(A) 申请公布日期 2010.02.16
申请号 KR20097026479 申请日期 2008.05.20
申请人 NOVARTIS AG 发明人 PFISTER KEITH B.;WAGMAN ALLAN S.;NG SIMON;SENDZIK MARTIN;SUTTON JAMES;WIESMANN MARION
分类号 C07D417/14;A61K31/437;A61P35/00;C07D413/12 主分类号 C07D417/14
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