发明名称 |
ORAL PREPARATION COMPRISING SPECIFIC ORGANIC ACID, AND METHOD FOR IMPROVEMENT IN ELUTION PROPERTY AND CHEMICAL STABILITY OF ORAL PREPARATION |
摘要 |
<p>Disclosed is a chemically stable oral preparation having an excellent elution property, which comprises a specific morphinan derivative or a pharmacologically acceptable acid addition salt thereof as an active ingredient. Specifically disclosed is an oral preparation which comprises a specific morphinan derivative or a pharmacologically acceptable acid addition salt thereof as an active ingredient, and additionally contains such an organic acid that 30 mL or more of water is needed for dissolving 1 g of the organic acid at 20°C. Also disclosed is a method for improving the elution property and the chemical stability of an oral preparation comprising a specific morphinan derivative or a pharmacologically acceptable acid addition salt thereof as an active ingredient, which comprises adding such an organic acid that 30 mL or more of water is needed for dissolving 1 g of the organic acid at 20°C to the oral preparation.</p> |
申请公布号 |
KR20100017119(A) |
申请公布日期 |
2010.02.16 |
申请号 |
KR20097024058 |
申请日期 |
2008.05.20 |
申请人 |
TORAY INDUSTRIES, INC. |
发明人 |
OHTA KOTOE;MINAKAMI SATOSHI;TOKUMITSUI HIROYUKI |
分类号 |
A61K47/12;A61K9/20;A61K31/485;A61P13/02 |
主分类号 |
A61K47/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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