发明名称 |
MODIFIZIERTES ADENOVIRUS-HEXON-PROTEIN UND ANWENDUNGEN DAVON |
摘要 |
The present invention provides a method of altering the specificity of an adenovirus vector. The method involves providing an adenovirus having a capsid with a modified adenovirus hexon protein. The modified adenovirus has a capsid comprising a hexon protein with a deletion in hypervariable region 1 and/or hypervariable region 4 of the hexon and an insert of an exogenous molecule therein. |
申请公布号 |
AT455558(T) |
申请公布日期 |
2010.02.15 |
申请号 |
AT20070835738T |
申请日期 |
2007.04.27 |
申请人 |
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA |
发明人 |
ROY, SOUMITRA;WILSON, JAMES |
分类号 |
A61K39/12 |
主分类号 |
A61K39/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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