DERIVATIVE OF PYRROLIDINE AND PIPERIDINE AS NK1 ANTAGONIST,申请号JP20090257558-传众专利搜索

发明名称	DERIVATIVE OF PYRROLIDINE AND PIPERIDINE AS NK1 ANTAGONIST
摘要	<P>PROBLEM TO BE SOLVED: To provide derivatives of pyrrolidine and piperidine as an NK1 antagonist. <P>SOLUTION: A pharmaceutical composition is an NK<SP>1</SP>antagonist having formula (I)(wherein Ar<SP>1</SP>and Ar<SP>2</SP>are phenyl or heteroaryl substituted if needed, X<SP>1</SP>is an ether, a thio, or an imino bond, R<SP>4</SP>and R<SP>5</SP>are not both H and alkyl, and other variables are as specified) and useful for the treatment of many disorders (including vomit, depression, anxiety, and cough), and a method of treatment and combination with other factors are also disclosed. <P>COPYRIGHT: (C)2010,JPO&INPIT
申请公布号	JP2010031053(A)	申请公布日期	2010.02.12
申请号	JP20090257558	申请日期	2009.11.10
申请人	SCHERING CORP	发明人	PALIWAL SUNIL;REICHARD GREGORY A;WANG QIANG;XIAO DONG;TSUI HON-CHUNG;SHIH NENG-YANG;ARREDONDO JUAN D;WROBLESKI MICHELLE LACI;PALANI ANANDAN
分类号	C07D207/14;C07D491/107;A61K31/357;A61K31/40;A61K31/401;A61K31/4015;A61K31/402;A61K31/4025;A61K31/4166;A61K31/4178;A61K31/4188;A61K31/421;A61K31/435;A61K31/4355;A61K31/437;A61K31/438;A61K31/445;A61K31/451;A61K31/454;A61K31/4545;A61K31/499;A61K31/505;A61K31/506;A61K31/537;A61K31/5377;A61K31/5383;A61K31/664;A61K45/00;A61P1/00;A61P1/08;A61P1/14;A61P3/04;A61P3/06;A61P3/10;A61P5/40;A61P9/10;A61P11/00;A61P11/06;A61P11/14;A61P13/10;A61P15/00;A61P17/00;A61P25/00;A61P25/02;A61P25/04;A61P25/06;A61P25/08;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P25/30;A61P25/32;A61P25/36;A61P27/02;A61P29/00;A61P31/18;A61P43/00;C07D207/26;C07D207/27;C07D207/273;C07D207/50;C07D211/28;C07D211/30;C07D211/32;C07D211/34;C07D211/42;C07D211/56;C07D211/60;C07D211/72;C07D211/76;C07D401/04;C07D401/12;C07D401/14;C07D403/04;C07D413/12;C07D471/10;C07D487/04;C07D487/10;C07D491/10;C07D498/10;C07D513/10	主分类号	C07D207/14
代理机构		代理人
主权项
地址