| 摘要 |
<P>PROBLEM TO BE SOLVED: To identify a molecule homable to a specific organ or tissue. <P>SOLUTION: There are provided a molecule selectively homing to various normal organs or tissues (including lung, pancreas, skin, retina, prostate, ovary, lymph node, adrenal gland, liver or gut) and a molecule selectively homing to tumor-bearing organs or tissues (including pancreas bearing pancreatic tumor or lung bearing lung tumor). Also, there are provided conjugates comprising an organ or tissue homing molecule linked to a moiety. Such functional group can be, for example, a therapeutic agent or a detectable agent. Further, there are provided a method of identifying a membrane dipeptidase (MDP)-binding homing molecule that selectively homes to lung endothelium. <P>COPYRIGHT: (C)2010,JPO&INPIT |
