| 发明名称 |
CALCIUM FLUX AS A PHARMACOEFFICACY BIOMARKER FOR INHIBITORS OF HISTONE DEACETYLASE |
| 摘要 |
Described herein are methods for using calcium flux as a biomarker to select and predict patients likely to respond to an apoptotic agent as therapy. Further described herein is a method of using calcium flux as a clinical biomarker to determine whether a tumor is sensitive to an HDAC inhibitor.
|
| 申请公布号 |
KR20100016524(A) |
申请公布日期 |
2010.02.12 |
| 申请号 |
KR20097023714 |
申请日期 |
2008.04.11 |
| 申请人 |
PHARMACYCLICS, INC. |
发明人 |
BALASUBRAMANIAN SRIRAM;BUGGY JOSEPH J.;RAMOS JASON;SIRISAWAD MINT |
| 分类号 |
G01N33/50;A61K38/18;G01N33/15;G01N33/52 |
主分类号 |
G01N33/50 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
