发明名称 STEREOSELECTIVE SYNTHESIS OF (S)-1-METHYL-3-PHENYLPIPERAZINE
摘要 This invention provides for a compound according to Formula (1), wherein R1 is methyl, ethyl, n-propyl, isopropyl, benzyl or 2-haloethyl and the use thereof in a method to prepare (S)-1-methyl-3-phenylpiperazine by enzymatic hydrolysis of the compound, followed by separation and cleavage of the oxalamic groups, whereby the protease of Streptomyces griseus is used as enzyme for the enzymatic hydrolysis.
申请公布号 US2010036126(A1) 申请公布日期 2010.02.11
申请号 US20070304557 申请日期 2007.06.14
申请人 N.V. ORGANON 发明人 VAN VLIET MICHIEL CHRISTIAN ALEXANDER;KEMPERMAN GERARDUS JOHANNES;SCHREUDER GOEDHEIJT MARCEL
分类号 C07D241/04;C12P17/12 主分类号 C07D241/04
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