发明名称 |
MONOCLONAL ANTIBODIES AGAINST TISSUE FACTOR PATHWAY INHIBITOR (TFPI) |
摘要 |
Isolated monoclonal antibodies that bind human tissue factor pathway inhibitor (TFPI) and the isolated nucleic acid molecules encoding them are provided. Pharmaceutical compositions comprising the anti-TFPI monoclonal antibodies and methods of treating deficiencies or defects in coagulation by administration of the antibodies are also provided. Methods of producing the antibodies are also provided.
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申请公布号 |
CA2733075(A1) |
申请公布日期 |
2010.02.11 |
申请号 |
CA20092733075 |
申请日期 |
2009.08.04 |
申请人 |
BAYER HEALTHCARE LLC |
发明人 |
WANG, ZHUOZHI;MURPHY, JOHN E.;PAN, JUNLIANG;JIANG, HAIYAN;LIU, BING |
分类号 |
C07K16/38;A61K39/395;A61P7/04;C12N15/13;C12P21/08 |
主分类号 |
C07K16/38 |
代理机构 |
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代理人 |
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地址 |
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