发明名称 |
IMIDAZOPYRIDIN-2-ON DERIVATIVE |
摘要 |
<p>A compound represented by formula (I) and having an mTOR inhibition activity or a pharmacologically acceptable salt of the compound. [In formula (I), A represents a 8- to 10-membered partially-saturated or aromatic dicycylic fused nitrogenated heterocyclic group having 1 to 3 nitrogen atoms; R1 represents a hydroxy group, a halogen atom, a cyano group, or the like; n represents an integer of 0 to 3; B represents a 3- to 7-membered monocyclic saturated or partially-saturated cyclic hydrocarbon group, provided that one or two oxygen atoms, sulfur atoms, nitrogen atoms and the like may be contained as a constituent or constituents of the ring; R2 represents a substituent located on a carbon atom or a nitrogen atom that constitutes B; m represents an integer of 0 to 3; Q represents a bond, or a C1-4 alkylene group; R3 and R4 independently represent a hydrogen atom, a halogen atom, a C1-4 alkyl group, or the like; and R5 and R6 independently represent a hydrogen atom, a halogen atom, a C1-4 alkyl group, or the like.]</p> |
申请公布号 |
WO2010016490(A1) |
申请公布日期 |
2010.02.11 |
申请号 |
WO2009JP63807 |
申请日期 |
2009.08.04 |
申请人 |
DAIICHI SANKYO COMPANY,LIMITED;OHTSUKA, MASAMI;HAGINOYA, NORIYASU;ICHIKAWA, MASANORI;MATSUNAGA, HIRONORI;SAITO, HIRONAO;SHIBATA, YOSHIHIRO;TSUNEMI, TOMOYUKI |
发明人 |
OHTSUKA, MASAMI;HAGINOYA, NORIYASU;ICHIKAWA, MASANORI;MATSUNAGA, HIRONORI;SAITO, HIRONAO;SHIBATA, YOSHIHIRO;TSUNEMI, TOMOYUKI |
分类号 |
C07D471/04;A61K31/437;A61K31/4709;A61K31/4725;A61P35/00;A61P35/02;A61P43/00;C07D519/00 |
主分类号 |
C07D471/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|