FIELD APPLICATION FOR MALARIA VECTOR CONTROL USING SUNLIGHT ACTIVE FORMULATED EXTRACT

摘要

This invention introduces an innovative modality for malaria vector control that combines both effectiveness and efficiency with the highest levels of human safety and environmental friendliness. The novelty of this patent lies in developing a new ecologically safe technology using a natural plant extract (photoactive porphyrine derivative) and mosquito larvae attractant (autolized yeast) as Sunlight- Active Formulated Extract (SAFE) against the three different species of mosquito larvae (Anopheles, Aedes and Culex). In this context, the accumulated photoactive compound (photosensitizer) in the larvae body induces, upon sunlight exposure, an oxidation stress that results in organism death. The obtained results revealed that SAFE is highly effective as it ensures 100% mortality of mosquitoes larvae. The effectiveness of SAFE accumulation in the larvae bodies was qualitatively and quantitatively investigated using the Confocal Laser Scanning Microscopy (CLSM) technique.