| 发明名称 |
Pharmaceutically Active Compounds |
| 摘要 |
Compounds of the formula (I): wherein R1, R2, R4 and R13 are as defined or a pharmaceutically or veterinarily acceptable salt or polymorph thereof, or a pharmaceutically or veterinarily acceptable solvate or pro-drug thereof: are potent and selective inhibitors of type 5 cyclic guanosine 3',5'-monophosphate phosphodiesterase (cGMP PDE5) and have utility in the treatment of, inter alia, male erectile dysfunction (MED) and female sexual dysfunction (FSD).
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| 申请公布号 |
US2010035891(A1) |
申请公布日期 |
2010.02.11 |
| 申请号 |
US20090469311 |
申请日期 |
2009.05.20 |
| 申请人 |
PFIZER INC |
发明人 |
BUNNAGE MARK EDWARD;DEVRIES KEITH MICHAEL;HARRIS LAURENCE JAMES;LEVETT PHILIP CHARLES;MATHIAS JOHN PAUL;NEGRI JOANNA TERESA;STREET STEPHEN DEREK ALBERT;WOOD ALBERT SHAW |
| 分类号 |
A61K31/496;C07D231/16;A61K;A61K31/519;A61P;A61P1/00;A61P3/10;A61P9/00;A61P9/04;A61P9/10;A61P9/12;A61P9/14;A61P11/00;A61P11/02;A61P11/06;A61P13/00;A61P13/02;A61P13/08;A61P13/10;A61P15/06;A61P15/08;A61P15/10;A61P17/00;A61P17/06;A61P17/14;A61P25/00;A61P25/02;A61P25/28;A61P27/02;A61P27/06;A61P35/00;A61P35/04;A61P37/08;A61P43/00;C07B61/00;C07D;C07D213/80;C07D213/803;C07D231/38;C07D401/04;C07D401/12;C07D401/14;C07D403/04;C07D487/04;C07F7/18 |
主分类号 |
A61K31/496 |
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