发明名称 |
DRUG DELIVERY COATING FOR USE WITH A MEDICAL DEVICE AND METHODS OF TREATING VASCULAR INJURY |
摘要 |
The present inventions provide various embodiments of medical devices coated with a therapeutic coating comprising a mTOR targeting compound and a calcineurin inhibitor, and methods of applying said coatings. In various aspects, the therapeutic coating comprises a bio-absorbable carrier component at least partially formed of a cellular uptake inhibitor and a cellular uptake enhancer, a mTOR targeting compound and a calcineurin inhibitor. In various aspects, the present invention provides for controlled delivery, which is at least partially characterized by total and relative amounts of a cellular uptake inhibitor and cellular uptake enhancer in a bio-absorbable carrier component.
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申请公布号 |
US2010034867(A1) |
申请公布日期 |
2010.02.11 |
申请号 |
US20060919363 |
申请日期 |
2006.04.28 |
申请人 |
ATRIUM MEDICAL CORPORATION |
发明人 |
HERWECK STEVE A.;MARTAKOS PAUL;MOODIE GEOFFREY;KARWOSKI THEODORE;CARLTON TREVOR |
分类号 |
A61L27/54;A61K31/436;A61K38/13;A61K47/12;A61L29/16;A61P9/00 |
主分类号 |
A61L27/54 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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