发明名称 |
PROCESS FOR PRODUCTION OF BICYCLO[2.2.2]OCTYLAMINE DERIVATIVE |
摘要 |
Disclosed is a production process which can synthesize a bicyclo[2.2.2]octylamine derivative (which can be used as an intermediate for the production of a pharmaceutical agent) efficiently under mild conditions in a large quantity. The bicyclo[2.2.2]octylamine derivative can be produced by cyclizing a compound represented by general formula (1) [wherein R1 represents an alkyl group having 1 to 6 carbon atoms which may have a substituent, an arylmethyl group which may have a substituent, or an arylethyl group which may have a substituent] with a compound represented by general formula (2): R2-NH2 [wherein R2 represents an alkyl group having 1 to 6 carbon atoms which may have a substituent, an aralkyl group which may have a substituent, a hydroxy group, an alkyloxy group having 1 to 6 carbon atoms which may have a substituent, or an aralkyloxy group which may have a substituent] and reducing the resulting product.
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申请公布号 |
CA2732984(A1) |
申请公布日期 |
2010.02.11 |
申请号 |
CA20092732984 |
申请日期 |
2009.08.07 |
申请人 |
KYORIN PHARMACEUTICAL CO., LTD. |
发明人 |
AKEBOSHI, TOMOHIRO;IRIYAMA, YUSUKE;KAWANAMI, HIROTAKA |
分类号 |
C07C227/16;C07C229/50;C07C251/20;C07C251/44;C07C309/66 |
主分类号 |
C07C227/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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