发明名称 |
METHODS AND SYSTEMS FOR PREDICTING PROTEINS THAT CAN BE SECRETED INTO BODILY FLUIDS |
摘要 |
<p>The present invention is directed to methods and systems for predicting protein secretion into bodily fluids. In an embodiment, a method uses a feature set comprising secretory properties of collected proteins to train a classifier, based on the feature set, to recognize protein features corresponding to proteins that are likely to be secreted into a biological fluid. Another method determines, using a trained classifier and identified features of a received protein sequence, the probability of the protein sequence being secreted into a biological fluid. In an embodiment, a system predicts the secretion of proteins into a biological fluid. The system comprises components configured to construct a protein feature set comprising properties of collected proteins, train a classifier to predict features of a protein that is likely to be secreted into the biological fluid, receive a protein sequence, and identify the received protein sequence as a secretory protein.</p> |
申请公布号 |
WO2010017559(A1) |
申请公布日期 |
2010.02.11 |
申请号 |
WO2009US53309 |
申请日期 |
2009.08.10 |
申请人 |
UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.;CUI, JUAN;PUETT, DAVID;XU, YING |
发明人 |
CUI, JUAN;PUETT, DAVID;XU, YING |
分类号 |
G01N33/00 |
主分类号 |
G01N33/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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