发明名称 |
NOVEL BENZOTHIAZEPINE AND BENZOTHIEPINE COMPOUNDS |
摘要 |
A pharmaceutical useful as a therapeutic agent and a preventive agent for hyperlipemia, and a pharmaceutical useful as a therapeutic agent and a preventive agent for hepatic disorders associated with cholestasis, particularly, primary biliary cirrhosis and primary sclerosing cholangitis, and a pharmaceutical useful as a therapeutic agent and a preventive agent for obesity, fatty liver and steatohepatitis are provided. A benzothiazepine or benzothiepine compound represented by the following formula (1A) having a thioamide bond and a quaternary ammonium substituent: (see formula 1A)
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申请公布号 |
CA2557576(C) |
申请公布日期 |
2010.02.09 |
申请号 |
CA20052557576 |
申请日期 |
2005.02.25 |
申请人 |
ASAHI KASEI PHARMA CORPORATION |
发明人 |
SASAHARA, TAKEHIKO;MOHRI, MITSUNOBU;KASAHARA, KEN-ICHI |
分类号 |
C07D281/10;A61K31/22;A61K31/366;A61K31/38;A61K31/381;A61K31/395;A61K31/4025;A61K31/428;A61K31/439;A61K31/4995;A61K31/5375;A61K31/541;A61K31/554;A61P1/16;A61P3/04;A61P3/06;A61P9/10;C07D285/36;C07D337/08;C07D409/12;C07D453/02;C07D471/08;C07D487/08 |
主分类号 |
C07D281/10 |
代理机构 |
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地址 |
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