发明名称 |
STABLE PHARMACEUTICAL COMPOSITIONS OF 2-AZA-BICYCLO[3.3.0]-OCTANE-3-CARBOXYLIC ACID DERIVATIVES |
摘要 |
A stable composition of a 2-aza-bicyclo[3.3.0]-octane-3-carboxylic acid derivative and a method for its preparation are described. The stable composition includes an intimate admixture of the derivative and a stabilizing effective amount of a lubricant. The stable composition further includes an external excipient. A method of preparing the stable composition includes forming an intimate admixture of the derivative and a lubricant and then blending the intimate admixture with at least one excipient. Preferably the final blend is transformed into solid unit dosage form.
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申请公布号 |
CA2530788(C) |
申请公布日期 |
2010.02.09 |
申请号 |
CA20042530788 |
申请日期 |
2004.06.24 |
申请人 |
TEVA PHARMACEUTICAL INDUSTRIES LTD |
发明人 |
HRAKOVSKY, JULIA;TENENGAUZER, RUTH |
分类号 |
A61K31/403;A61K9/14;A61K9/16;A61K9/20;A61K9/26;A61K47/14 |
主分类号 |
A61K31/403 |
代理机构 |
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主权项 |
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地址 |
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