发明名称 |
Polynucleotides encoding fully human antibodies against human 4-1BB |
摘要 |
Fully human antibodies and antigen-binding portions thereof that bind to human 4-1BB and that allow binding of human 4-1BB to a human 4-1BB ligand. In one aspect, the antibody is an IgG4 antibody. Also provided is a method for treating a disease in a subject comprising administering a therapeutically effective amount of the antibody to said subject.
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申请公布号 |
US7659384(B2) |
申请公布日期 |
2010.02.09 |
申请号 |
US20070903106 |
申请日期 |
2007.09.20 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
JURE-KUNKEL MARIA;HEFTA LAURA J.;SANTORO MARC;GANGULY SUBINAY;HALK EDWARD L. |
分类号 |
C07H21/00;A61K39/00;C07K16/28;C12N5/16;C12N15/63;C12P21/02 |
主分类号 |
C07H21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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