发明名称 |
Binding of pathological forms of prion proteins |
摘要 |
Infective aggregating forms of proteins such as PrP, amyloid, and tau are bound selectively in the presence of the normal form protein using a polyionic binding agent such as dextran sulphate or pentosan (anionic), or polyamine compounds such as pDADMAC (cationic) under selective binding conditions including the use of n-lauroylsarcosine at mildly alkaline pH, and may then be assayed.
|
申请公布号 |
US7659076(B2) |
申请公布日期 |
2010.02.09 |
申请号 |
US20040506131 |
申请日期 |
2004.08.27 |
申请人 |
MICROSENS BIOPHAGE LIMITED |
发明人 |
LANE AMIN R.;STANLEY CHRISTOPHER J.;WILSON STUART M. |
分类号 |
G01N33/53;G01N33/68;A61K31/715;A61K31/795;C07K1/22;C07K14/47;C08B37/02 |
主分类号 |
G01N33/53 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|