发明名称 INTERMEDIATE COMPOUND OF 3-HETEROARYL-3,5-DIHYDRO-4-OXO-4H-PYRIDAZINO[4,5- B]INDOLE-1-ACETAMIDE DERIVATIVES
摘要 The invention provides compounds of general formula (I) in which X represents a hydrogen or halogen atom; R<SUB>1 </SUB>represents a hydrogen atom or a (C<SUB>1</SUB>-C<SUB>4</SUB>)alkyl group; R<SUB>2 </SUB>and R<SUB>3 </SUB>each independently of one another represent a hydrogen atom or a (C<SUB>1</SUB>-C<SUB>4</SUB>)alkyl group, or else R<SUB>2 </SUB>and R<SUB>3</SUB>, together with the nitrogen atom bearing them, form a pyrrolidinyl, piperidinyl, morpholinyl or 4-(C<SUB>1</SUB>-C<SUB>4</SUB>)alkylpiperazinyl group; and Het represents a heteroaromatic group of pyridinyl, quinolinyl, isoquinolinyl, pyrimidinyl, pyrazinyl or pyridazinyl type which may carry one or more halogen atoms and/or one or more (C<SUB>1</SUB>-C<SUB>4</SUB>)alkyl and/or (C<SUB>1</SUB>-C<SUB>4</SUB>)alkoxy groups; in the form of bases, addition salts with acids, solvates or hydrates; the pharmaceutical compositions comprising them, processes for preparing them, and synthesis intermediates.
申请公布号 HK1102371(A1) 申请公布日期 2010.02.05
申请号 HK20070108859 申请日期 2005.10.04
申请人 SANOFI-AVENTIS 发明人 FROISSANT, JACQUES;MARABOUT, BENOIT;MARGUET, FRANK;PUECH, FREDERIC
分类号 A61K31/5025;A61K31/503;A61K31/5377;A61P3/10;A61P9/00;A61P9/04;A61P9/08;A61P9/10;A61P13/12;A61P17/00;A61P17/04;A61P17/06;A61P25/00;A61P29/00;A61P35/00;A61P37/02;C07D;C07D209/00;C07D209/18;C07D209/42;C07D241/00;C07D487/02;C07D487/04 主分类号 A61K31/5025
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