发明名称 preparation method of galactosyl-has magnetic nanoparticles containing adriamycin
摘要 Preparation of galactose albumin adriamycin magnetic nanoparticles: in order to prepare galactose albumin magnetic nanoparticle, cottonseed oil and magnetic nano powder is needed. Mix galactose albumin, adriamycin and magnetic nanoparticle at a proportion, and get the particle through emulsification in cottonseed oil, heating for solidification, and diethyl ether washing. This invention couples galactose to the surface of nanoparticle to form galactose nanoparticle, which targets actively and passively to improve the drug targeting level to liver. Modifying albumin adriamycin magnetic nanoparticles with galactose enhances its targeting level.
申请公布号 US2010029546(A1) 申请公布日期 2010.02.04
申请号 US20040663201 申请日期 2004.09.24
申请人 ZHANG YANGDE 发明人 ZHANG YANGDE
分类号 A61K38/38;A61P35/04;C07K1/107 主分类号 A61K38/38
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