摘要 |
Indirubin derivatives of formula (I) wherein R represents - (A)n- R1 or -CO-N(R2,R3) with A being C1-C5 alkylene group, optionally substituted by one or several A1 radical, A1 being an halogen Br, OH, OR4 or NH2, R4 being C1-C5 alkyl; - R1 being halogen, OH, N(R2, R3); R2 and R3, identical or different, being C 1 -C5 alkyl, optionally substituted by A1 such as above defined, or R2 and R3 are part of a cycle with 5 or 6 elements optionally comprising another heteroatom such as O or N; n = 1-5. It also relates to the biological application thereof.
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申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) |
发明人 |
MEIJER, LAURENT;SKALTSOUNIS, LEANDROS;MIKROS, EMMANUEL;MAGIATIS, PROKOPIOS;JOHNSON, CARL |