<p>The present invention belongs to the field of chemical synthesis and relates to an improved process for the preparation of paliperidone and its pharmaceutically acceptable salts as an active ingredient of a medicament for treatment of schizophrenia. It relates also to a process of crystallization of paliperidone and to the dihydrate form of the compound.</p>
申请公布号
WO2010014047(A1)
申请公布日期
2010.02.04
申请号
WO2009SI00032
申请日期
2009.07.30
申请人
KRKA, D.D., NOVO MESTO;RUZIC, MILOS;PRUDIC, DARJA;PECAVAR, ANICA;SMRKOLJ, MATEJ
发明人
RUZIC, MILOS;PRUDIC, DARJA;PECAVAR, ANICA;SMRKOLJ, MATEJ