发明名称 |
1-CYANOCYCLOPROPYL-DERIVATIVES AS CATHEPSIN K INHIBITORS |
摘要 |
The present invention relates to compounds of formula (I) and compositions for treating diseases associated with cysteine protease activity. The compounds are reversible inhibitors of cysteine proteases, including cathepsins B, K, C, F, H, L, O, S, W and X. Of particular interest are diseases associated with Cathepsin K.
|
申请公布号 |
WO2009001129(A9) |
申请公布日期 |
2010.02.04 |
申请号 |
WO2008GB50486 |
申请日期 |
2008.06.24 |
申请人 |
ASTRAZENECA AB;ASTRAZENECA UK LIMITED;DOSSETTER, ALEXANDER, GRAHAM;HERON, NICOLA, MURDOCH |
发明人 |
DOSSETTER, ALEXANDER, GRAHAM;HERON, NICOLA, MURDOCH |
分类号 |
C07D471/04;A61K31/4353;A61P19/02;A61P19/08;C07D471/10;C07D471/14;C07D491/04;C07D491/147 |
主分类号 |
C07D471/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|