发明名称 |
Pharmaceutical Formulation Comprising Metformin and Repaglinide |
摘要 |
The invention is related to a pharmaceutical composition comprising repaglinide in combination with metformin or a salt thereof in unit dosage form wherein a pre-formulation of the repaglinide has a pH independent dissolution profile and a relative humidity of less than about 25% prior to mixing with the metformin or a salt thereof; and optionally one or more pharmaceutically acceptable excipients and to a method for its preparation. |
申请公布号 |
US2010029721(A1) |
申请公布日期 |
2010.02.04 |
申请号 |
US20070442432 |
申请日期 |
2007.09.28 |
申请人 |
NOVO NORDISK A/S |
发明人 |
HOJGAARD BENT;KNUDSEN BREIAN;RASMUSSEN STELLA RUDKJAER;JACOBSEN LENE ORUP |
分类号 |
A61K31/451;A61P3/10 |
主分类号 |
A61K31/451 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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