METHOD OF PROMOTING NEUROGENESIS BY MODULATING SECRETASE ACTIVITIES

摘要

This invention provides methods and reagents for promoting neurogenesis, by modulating neural stem cell proliferation and differentiation. Particularly, this invention provides methods and reagents for promoting neurogenesis in a patient's central nervous system where the patient suffers from an aging-related neurodegenerative disease. Specifically, the invention provides methods for promoting neurogenesis comprising modulating the a and/or ?-secretase activities.