发明名称 USE OF SUBSTITUTED GLYCERIN DERIVATIVES FOR PRODUCING A PHARMACEUTICAL PREPARATION
摘要 A compound of the formula (1) or pharmaceutically acceptable salts thereof can be used for producing a pharmaceutical preparation for preventing or treating cancerous diseases, pathological sequelae of alcohol abuse, viral hepatitis, steatohepatitis, acute and chronic pancreatitis, toxic renal disorders, hepatic insulin resistance in diabetes mellitus, liver damage associated with Wilson's disease and/or sideroses, ischemic reperfusion damage, for use as an antidote to environmental toxins and prescription drug intoxication, for prolonging the retention time of drugs in the organism, and/or for combating toxic side effects on administration of chemotherapeutic agents. B6, B7 and B8 are identical or different and denote O, S, NH, PO4, Se, SO4. R1 is identical to H or a C6 and/or C7 to C26 and/or C20 alkyl chain; and R2, R3, R4 and R5 can be identical or different and denote an H or a C1 to C3 alkyl, alkanol, alkylamine and/or alkyl thiol group. R6, R7 and R8 can be identical or different; and H can denote a substituted or unsubstituted C6 and/or C7 to C26 alkyl radical, a glycoside radical, a positively or negatively charged amino acid radical, a -(CH2)n-N+ (R9, R10, R11), where R9, R10, R11 is H, methyl, ethyl and/or propyl radical, and where at least two of R2, R3, R4, and R5 can together form a polyol radical, and n denotes a whole number from 1 to 5.
申请公布号 US2010028417(A1) 申请公布日期 2010.02.04
申请号 US20070298174 申请日期 2007.04.27
申请人 MUELLER-ENOCH DIETER;HAEHNER THOMAS 发明人 MUELLER-ENOCH DIETER;HAEHNER THOMAS
分类号 A61K31/4178;A61K9/127;A61P3/06;A61P35/00 主分类号 A61K31/4178
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