发明名称 |
Products and processes for modulating peptide-peptide binding domain interactions |
摘要 |
The present invention relates to therapeutic compounds and methods of use of these therapeutic compounds for treating cellular proliferative disorders. The invention also provides three-dimensional structures of a Polo-like kinase and methods for designing or selecting small molecule inhibitors using these structures, and the therapeutic use of such compounds. The invention also includes a method for identifying novel phosphopeptide-binding domains.
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申请公布号 |
US2010030543(A1) |
申请公布日期 |
2010.02.04 |
申请号 |
US20080229797 |
申请日期 |
2008.08.27 |
申请人 |
YAFFE MICHAEL B;ELIA ANDREW E H;RELLOS PETER;CANTLEY LEWIS C;SMERDON STEPHEN J;MANKE ISAAC |
发明人 |
YAFFE MICHAEL B.;ELIA ANDREW E. H.;RELLOS PETER;CANTLEY LEWIS C.;SMERDON STEPHEN J.;MANKE ISAAC |
分类号 |
G06G7/48;A61K38/00;C07K14/47;C12N9/12;C12N15/10;G01N33/53;G06F19/00 |
主分类号 |
G06G7/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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