| 摘要 |
A novel method of imaging, comprising administration of a radioactive mono-cation, such as, for example, 82Rubidium (positron imaging) or Thallium (SPECT or planar imaging), in combination with a receptor binding ligand that stimulates the influx of cations. The method permits imaging of receptor-expressing tissue. However, unlike imaging methods which rely on a radiolabeled binding ligand, in the instant method the influx of the radioactive mono-cation is measured, not the binding of a radiolabeled ligand. Thus, there is a decreased likelihood of receptor saturation and potentially less radiation exposure for the patient.
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